Functional Genomics Core

RRID:SCR_023433

Becoming a core user

The Functional Genomics Core provides all of our Instruments, Services, and Consumables using the iLab system. It is not possible for researchers to use any of our items without an iLab account.

Policy

RII Core Facilities Pilot Program - May 3, 2023 Deadline

Date of publication

The RII Core Facilities Pilot Program is designed to support three key types of activity within the RII-managed core facilities. Each CFPP proposal will be evaluated on scientific merit and feasibility, and should focus on one or more of the following activity types:

  1. The development of new methods or techniques that would extend the standard operating procedures and capabilities of RII-managed core facilities and potentially impact multiple UA researchers.
  2. The acquisition of preliminary data needed for extramural proposals. Successful projects will result in at least one new extramural research proposal.
  3. The technical training of students conducting research under existing extramural funding. Proposals to train students from traditionally marginalized groups will be given funding priority.

Most awards will be capped at approximately $10,000, although well-justified projects may be awarded funding above this level. It is required that CFPP proposals and their budgets be developed with the assistance of the relevant core facility manager(s). Proposals are due May 3, 2023 by 5pm. List of eligible facilities:

  1. Analytical and Biological Mass Spectrometry
  2. Flow Cytometry and Human Immune Monitoring Shared Resource (BD LSR, BD, FACSARIA, BD Canto)
  3. Functional Genomics Core
  4. Imaging Cores - Electron
  5. Imaging Cores - Optical
  6. Machining and Welding Center
  7. Micro/Nano Fabrication Center
  8. Translational Bioimaging Resource
  9. University of Arizona Genetics Core
  10. BIO5 Genetically Engineered Mouse Models (GEMM) Core
  11. Arizona Genomics Institute

Application and Full Details

Discover BIO5 March 8th 2023

Date of publication

The DISCOVER BIO5 event series is designed to showcase the innovative bioscience research happening at the University of Arizona, and to share the inspiring ways we are preparing our next generation of scientists for the future. The 2023 Event is Wednesday, March 8th from 4PM-7PM. Registration is now closed.

RNAi screening

The FGC has purchased the  Ambion® Complete Human Genome Silencer® Select siRNA library. This library contains three constructs per target (64,752 constructs). The Ambion Silencer Select siRNAs are designed using their most advanced algorithm developed using a machine learning approach. In addition the siRNAs are chemically modified to enhance guide strand bias. This has the effect of maximizing siRNA silencing potency and for decreasing passenger strand related off-target effects. We will be happy to work with you to optimize the transfection protocols for your system and perform screens of the full genome or smaller sets.

Using our Biomek robots we can create custom sub-libraries from our collection to perform targeted small screens of the genes of your choosing.

 

Facility Email: fgc@arizona.edu

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Silencer Select siRNA library
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