"Covaris Adaptive Focused Acoustics (AFA) technology is firmly established as the fragmentation method of choice for NGS, and Covaris continues to innovate the tools required to shear DNA and RNA without GC bias or thermal damage.
The Covaris AFA process is conducted under isothermal conditions, ensuring the integrity of the nucleic acid sample is maintained and providing high recovery of double-stranded DNA during the shearing process.
Combined with the specifically engineered AFA Tubes it is possible to precisely and accurately fragment DNA and RNA to the 100 – 1500bp range (microTUBE), or 2 – 5kb range (miniTUBE)."
Text Credit:https://www.covaris.com/dna-rna-shearing-for-ngs/
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AZGC uses Covaris Ultrasonicator to shear genomic DNA prior to DNA Library Prep Protocols.
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