The TBIR manages a 7T Bruker Biospec research MRI scanner. Users can perform physiological and functional imaging of soft tissue anatomy, tumor growth, angiogenesis, cellularity, inflammation, myelination, myocardial function, early therapeutic effects, extracellular pH, redox state, and other applications. 3D anatomical imaging of soft tissues is performed at up to 300 μm resolution. The facility has technical support to aid in surgical procedures and anesthesia, protocol modifications and compliance, safety training, and consultations.
A Cubresa NuPET MRI compatible PET insert enables evaluation of tumor therapy response through diffusion-weighted MRI with PET tracers specific for tumor proliferation. The PET insert can also improve tumor detection through diffusion-weighted and T2-weighted MRI with PET tracers for specific biomarkers as well as evaluate drug delivery and perfusion for molecular theranostics assessments.